This workshop is designed to introduce the major applications of microscopy in pharmaceutical development: polymorphism, particle size analysis, contaminant identification, and glass corrosion.
Details
Please contact us if you would like to take this workshop.
Targeted Participants
This course is intended for the intermediate level analyst who is skilled at some of the microscopy techniques but needs training in other techniques and in interpretation.
Format
Lecture, demonstration and hands-on practice, as well as round table table tips and tricks discussion. Participants are encouraged to bring their own samples, if possible.
Main Curriculum
- Polymorphism: using Polarized light and thermal microscopy
- Ir and Raman Microspectroscopy
- Size and shape analysis: using OLM, SEM/EDS, and fluorescence with image analysis
- Contamination identification and glass corrosion analysis: using polarized and scanning microscopes
- EDS and Microspectroscopy
Instruments Available
- Polarizing Light Microscope
- Hitachi S3500 SEM
- COXEM SEM EM-30N
- Image Analysis Software
- Linkam Thermal Microscope
- Bruker Esprit (SDD)
- IR and Raman Microscopes
Enrollment Note
Registration will be limited to a maximum of 15 participants.
EMS will provide samples to those who prefer not to bring their own.
Pharmaceutical Microscopy: Applications
This workshop is designed to introduce the major applications of microscopy in pharmaceutical development: polymorphism, particle size analysis, contaminant identification, and glass corrosion.
The workshop is conducted over three days with a mixture of theory, demonstrations and hands-on work. The course is designed to prepare the student to apply microscopy to solve solid-state pharmaceutical issues. The emphasis is on the practical use of the microscope.Robert Carlton
Robert worked for nearly 40 years in the research and development of fiberglass insulation, orthopedics, and pharmaceuticals. His specialty is solid-state analysis with a particular interest in microscopy. Robert retired from full-time employment in early 2016. He is now teaching microscopy and consulting on solid-state analysis in pharmaceutical development. Robert's education is in chemistry, with a Ph.D. from Lehigh University. He has taken numerous courses at McCrone Research Institute on microscopy from Skip Palenik and Walter McCrone. Robert worked for pharmaceutical companies Rhone-Poulenc Rorer (Aventis, Sanofi), Elan (Nanocrystal), and GlaxoSmithKline in microscopy and solid-state analysis for 24 years. He published a book on Pharmaceutical Microscopy in 2011 with Springer.Michael Kostrna
Michael was the program director of the Electron Microscopy Technician program at Madison Area Technical College and has more than 35 years in EM technical education and research experience. He has been training EM students for 30 years and has developed curricula and lab exercises for TEM, SEM, OLM, lab safety, introductory and advanced biological EM, EM, maintenance, and x-Ray microanalysis. He has worked with companies such as SC Johnson Polymer, Dow Chemicals, Io Genetics, Virent Technologies, ABS Global, NanoOnocology, and Microscopy Inovations, and in the process gained insight to the various applications of EM.Al Coritz
Al has been working in the Electron Microscopy field for 39 years, beginning at the Yale School of Medicine and ending up on the commercial side with several key EM companies. His specialty is Cryo-techniques and Thin Film Technology: i.e. Freeze Fracture/Rotary Shadowing, High Pressure Freezing, and more. He is currently with Electron Microscopy Sciences where he has been the Technical Director for over 20 years.